According to the National Institute on Drug Abuse (NIDA), prescription stimulants are commonly misused among young adults and college students. In 2020, approximately 6.5% of full-time college students reported nonmedical use of prescription stimulants in the past year.
Cocaine use remains a significant concern in the USA, with an estimated 5.5 million Americans aged 12 or older reporting past-year cocaine use in 2020, according to the Substance Abuse and Mental Health Services Administration (SAMHSA). Cocaine use can lead to addiction, cardiovascular problems, and other health issues.
Methamphetamine, a potent and highly addictive stimulant, has become a growing problem in certain regions of the USA. In 2020, approximately 1.9 million Americans aged 12 or older reported past-year methamphetamine use, according to SAMHSA. Methamphetamine use is associated with serious health consequences, including addiction, psychosis, and dental problems ("meth mouth").
While opioids are the primary drivers of drug overdose deaths in the USA, stimulant-involved overdose deaths have also been increasing in recent years. According to the CDC, the number of drug overdose deaths involving psychostimulants such as methamphetamine and cocaine more than doubled from 2015 to 2020.
Stimulant use can have various health risks and consequences, including increased heart rate and blood pressure, irregular heartbeat, seizures, stroke, and psychiatric symptoms such as paranoia and psychosis. Long-term stimulant use can lead to addiction, cognitive impairment, and other adverse health outcomes.
Individuals struggling with stimulant use disorders may benefit from treatment and support services. Behavioral therapies, such as cognitive-behavioral therapy (CBT) and contingency management, have been shown to be effective in treating stimulant addiction. However, there is currently no FDA-approved medication specifically for the treatment of stimulant use disorders.
Harm reduction strategies, such as access to naloxone (a medication used to reverse opioid overdoses), syringe exchange programs, and drug checking services, may help reduce the risk of overdose and other negative consequences associated with stimulant use.
Prevention efforts aimed at reducing stimulant use include public education campaigns, school-based prevention programs, and efforts to restrict access to prescription stimulants and illicit drugs.
Stimulants can elevate heart rate and blood pressure, which may pose risks for individuals with cardiovascular conditions.
Stimulants can suppress appetite, leading to weight loss and nutritional deficiencies, particularly with chronic use.
Stimulants can disrupt sleep patterns and lead to difficulty falling asleep or staying asleep.
Stimulant use may cause dry mouth (xerostomia), which can contribute to dental problems such as tooth decay and gum disease.
Some individuals may experience excessive sweating or perspiration as a side effect of stimulant use.
Stimulants can enhance alertness, attention, and energy levels, which may be desirable effects for some individuals but can also lead to agitation or restlessness.
Stimulants can induce feelings of euphoria or pleasure, particularly at higher doses or with certain drugs like cocaine or methamphetamine.
Stimulant use may exacerbate anxiety symptoms or trigger feelings of paranoia, particularly with higher doses or in susceptible individuals.
Some individuals may experience agitation, irritability, or mood swings as a result of stimulant use.
In some cases, particularly with high doses or prolonged use, stimulants can induce psychotic symptoms such as hallucinations, delusions, and disorganized thinking.
Stimulant use may trigger headaches or migraines in some individuals.
Stimulants can cause involuntary muscle movements or tremors, particularly at higher doses.
Chronic stimulant use may lead to sexual dysfunction or decreased libido in some individuals.
Long-term use of stimulants can increase the risk of cardiovascular complications such as heart rhythm disturbances, heart attacks, and strokes.
Prolonged use or misuse of stimulants can lead to physical dependence and addiction, characterized by compulsive drug-seeking behavior and withdrawal symptoms upon cessation.
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